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Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it one should err on the side of caution and allow the FDA do its job and demand some investigation be done so the public understands the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on their own medications. Researchers found out that participants taking this drug for a year, dropped a few pounds within four weeks and have kept the load off throughout the 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which are made up of many active ingredient, which may make them more effective and safer. Combo-pilling may be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular will be the fact that by right now there aren't any long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heartbeat, and shouldn't be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation. The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.