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Some possible triggers may include: Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it one should err on the side of caution and permit the FDA do its job and demand some study be done so your public knows the side effects and hazards of the medications before we drive them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on their medications. Researchers found that participants using this drug for a year, lost excess weight within a month and have kept the load off throughout the 56 weeks in the study. Contrave is really a combination of the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, which can make them more potent and safer. Combo-pilling is the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that by right now there aren't long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure levels and heart rate, and mustn't be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure, in addition to by a person with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. Most of the combinations which can be used to enhance weight-loss involve an amphetamine and an antidepressant. Phentermine and Prozac are a popular combination that have been around for a long time, although it has been around my own mail to truly combine both the and try to get FDA approval to showcase it as a weight loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies should not be involved in combining medications and selling them something must be wrong while using combination. In fairness there is certainly one fat loss combination pill that is certainly in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and substance abuse, using the antidepressant bupropion (Wellbutrin, Zyban) many experts have given the try to move forward by an FDA advisory committee, but as of yet hasn't been approved.