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Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you ought to err to the side of caution and permit the FDA do its job and demand some research be done in order that the public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications. Researchers discovered that participants investing in this drug for the year, lost excess weight within one month and have kept the load off through the entire 56 weeks from the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of many active ingredient, that might make them far better and safer. Combo-pilling is the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that at the time of right now there aren't long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure and heartbeat, and really should not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. "This will be the first drug I'm conscious of that targets both the appetite and reward centres inside the brain," he was quoted saying.